The draft human genome sequence, announced in 2000 promised great insights into human biology, medicine and evolution. To celebrate the 10th anniversary, Nature has repackaged the Human Genome at Ten news special into a free iPad App. In this special, Nature asks whether the sequence has delivered the insights that were anticipated, and what lessons have been learned from the first post-genome decade. Human genetics in 2010 looks infinitely more complex, and questions about how to make sense of the explosion in biological data are only becoming more pressing. The Nature Human Genome iPad special edition contains landmark research as well as exclusive video commentary from Nature's genetics editor, who discusses the past, present and future of genomics. In addition, the App features an interactive graph displaying a timeline of human genome research over the past ten years and includes audio clips from authors discussing their papers.